but I doubt it because the mask is a family heirloom of sorts going back several generations to an ancestor that was forced to wear it as a punishment for crimes against the state. There's an episode of the cartoon in which lady Jaye goes to visit the castle of her ancestors and runs into Lady Jaye there.
In that episode you find out more about the mask and how it came to be on Destro's face all the time.
Then, in the Devil's Due comic that brought the franchise back to the comic world, Destro's son uses the mask as part of an attempt to pass himself off as his father. You find out a bit more about the mask there, too. Although it's not quite the same storyline.
So I am hoping that they find a way to incorporate the mask somehow, because it was so metonymical with Destro - it's iconic - that I would've expected Eccleston to be wearing the mask at all times. And I've yet to see it once.
I'm hoping, though, that there's a surprise in store and he'll end up donning it before the credits roll.