anyone familiar with setting mtu size?

1464 is a weird number to work with. 1500 is generally the baseline for most small networks (windows default is 1500). i concur with buzd, this is a setting that i normally wouldn't want to change unless i had to. now, if you are working with 10 gb/fcoe etc and using jumbo frames, then yeah, i'd see cause for concern.

you can ping from cmd line using "ping xxx.xxx.xxx.xxx -f -l 1500" to determine if the packets are going where you want them to without need of fragmentation. the xxx.xxx.xxx.xxx is obviously the IP/url, the -f forces full packet without fragmentation, and the -l is the mtu size. you can start with whatever size and keep subtracting from the number (generally go down by 10) until the reply is successful. then you add 24 (? maybe 28 i don't really remember :() to the number. the ping without fragmentation is a good indicator of the range you need to be in though.

there is some really good cisco documentation out there on it, i'll look to see if i can find it.