Akeem Hicks case for playing 3-4 DE.

Are we expecting Hicks to take on the Guard and Center as a Nose, lots of one on one which I guess would fit as a RE. Really not sure where he would be best Nose or RE. Appears to be more of a numbers game opposed to putting players where they have the most potential.
In your base defense, you guard and your center HAS to duo block the nose or your center will end up in the backfield (Bunkley did this to Nick Mangold - All-Pro center - in the 2011-2012 season). Now on pass downs you'll see the a blocker 1on1 with the nose because he isn't a pass rushing threat (unless you have one of those Ngata type freaks). That has been my whole point, Hicks is strong like a nose (so single-blocking him isn't a good idea), but he has a pass rush also. Put him at 3-tech and you make the offense make a decision: play him 1on1 and risk your guard getting dominated; double team him and your nose is free to destroy your guard. This is all base defense here and I think Hicks slide on nickel down possibly.

Guys like this change the offensive gameplan, assuming Hicks continues to develop at the pace that he has thus far.