Louisiana food in NYC
After having lived in Jersey and worked in the city for 15 years, let me assure not to bother looking for ANY Cajun/Creole food in Manhattan.
Enjoy some Italian food and Chinese like you can't get anywhere else instead. Go to Mulberry street and take your pick of the Italian restaurants. You literally cannot go wrong. All are fantastic and most of them are much cheaper than any other restaurant in the city.
Chinese is good pretty much everywhere, though I will warn you the ones with ducks hanging in the window are EXTREMELY authentic Chinese - and by that I mean they serve the bland Cantonese stuff. If you like spice, don't go to those. Also, many excellent Greek restaurants. Try Niko's Mediterranean Grill on the West side, Broadway at 77th.