There’s Something About Mary. The entire sequence when the dog is on speed. From when he first attacks Ted, to when he jumps out the window. I was crying in the theater.
Almost posted Mary
It’s actually a very impactful movie for me - it was the movie I went to after breaking off a 7 year relationship
Those were very cathartic laughs
Similarly, 40 yr old virgin is what my (now) wife and I saw after evacuating for Katrina- that helped too