Literature:
Grand Admiral Thrawn
MacBeth
Professor Moriarty
Literature/Stage:
Scarpia
Javert
Literature/Film:
Nurse Ratched
Hannibal Lecter
Film:
Hans Gruber
Darth Vader (in episodes IV, V, and Rogue One)
Television:
Wilson Fisk (Vincent D'Onofrio)
Spike
The Gentlemen
The Borg