What is the rep meter?
I think people need to respect other people's opinions and not necessarily give negative reputation for it. I can imagine a few situations where if you don't agree with the majority of people on the board then you will get a ton of negative reputation.
It might even happen with some of the joke posts around here where some people get mad and don't realize that it's satire, although I do think it will more than balance out from people who actually get the joke and give positive rep.
It will be interesting to see how this plays out.