Can anyone guess ways to continue to be successful with Brees?

Icon said

You mean the second interception where Kamara ran the wrong route, and the third that was courtesy of Jared Cook?

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While none of us will know if AK ran the wrong route or if it was an option route and they didn’t read it the same. If you watch the replay and it was an option route, AK ran the right one because he was wide open and Drew only had to toss the ball over Devin White’s head.