Young couple goes on van tour of US, boy comes back with van - no girl

He doesn't seem like the 'off himself' type.
But I do see the possibility of him being attacked while trying to sleep in a state of exhaustion by some of the large reptiles in that reserve.

Finding "remains" could mean a lot of things. But since I read some quotes referring to "partial remains", that's likely a sign that (whether already deceased or not) there was some 'feasting' that took place on Brian.

As hilarious as gators devouring him alive would be, I think it's more likely he killed himself and then the remains got picked clean over him getting Timothy Treadwell'd.