This is the kinda stuff that irks me. You’re trying to personify the needs of the immune system with what a person who is tired would need.
Your immune system doesn’t need a “break.” It needs practice, preferably against dummy targets rather than live bullets. The best chance for reducing immune system pressure is to give it the blueprint for easy victories and not letting it forget the blueprint.
Your immune system fights off millions of germs every single day. You might as well give it the target practice for the ones that can actually do damage.