COVID-19 Outbreak Information Updates (Reboot) [over 150.000,000 US cases (est.), 6,422,520 US hospitilizations, 1,148,691 US deaths.]

One of the lingering mysteries of the COVID-19 pandemic is why some people get infected without getting sick and others don't get infected at all, despite exposure.

Beyond a few known risk factors, it's mostly dumb luck that determines how someone will fare if they are exposed to the virus that causes COVID-19, a handful of researchers said.

But they're still trying for more scientific answers by studying people who are intentionally exposed to the virus and those who escape its effects.

People like Faith Paine.

Paine, 26, of London, volunteered for a "challenge trial" – meaning researchers dribbled the virus that causes COVID-19 up her nose, intending to get her sick.

For 17 days last year, she had to stay in a single room in London's Royal Free Hospital, unable to leave, exercise or see anyone who wasn't encased in a hazmat suit. The food was the worst part, she said, ordered ahead for her entire stay and more appropriate for an airplane ride than a regular diet.

Between all the poking and prodding, she was allowed to go to bed only after 11:30 p.m., and was awakened by 6:30 a.m. She felt awful the whole time, but she wasn't sure whether it was because of the lack of sleep and mediocre food, or because she had COVID-19.

She didn't.

Like half of the 36 U.K. residents paid about $6,500 to be willingly exposed to COVID-19, she never developed an infection and never shed virus.

Dr. Andrew Catchpole, who helped lead the research, said he didn't expect everyone to get sick. He runs regular challenge trials for infections like the flu and always aims for about 50% to 70% to fall ill, to ensure he is giving enough, but not an unsafe amount of virus.

But it didn't take much virus to give those 18 people COVID-19, and though data is still being analyzed, they have yet to identify a clear reason why the others didn't catch..........

https://www.msn.com/en-us/health/me...sedgntp&cvid=97ab1c5711714f149cf708709bc782f9