Each of these has something to recommend it, except the upper-right. That one's just a deadeyed video game side-character.
Upper-left looks much more real. Especially the chair.
The bottom-right has better articulation in the finger and lips. A better impression of an iris in the eyes, but his right hand is a blob and the clothes/chair are clearly CGI.
Bottom-left, the clothes. They're real, little bits of fuzz, uneven shadows, dappled light on the shoulder. That there is a real thing wearing real clothes, sitting in a real chair. Too bad it's blind and has arthritis.