I think that people, in general, are too stupid to protect themselves even if there is complete transparency and everything that they need is provided for them. There could have been a proven vaccine available a decade in advance with with a multi-month warning and the same people who have refused would have refused.
Example: We know that seatbelts save lives and limit injuries. The seatbelts are provided for us. We are educated about their use and effectiveness. We are mandated to use them. Automotive manufacturers install safeguards on some vehicles that prevent operation without them in use.