I agree on rhythm, but how well the offense is executing early in the game will dictate rhythm for the rest of the game. It’s hard for one play to set up the next when the first couple of series are failures, the defense isn’t adjusting to what you’re doing well (because you’re doing nothing well) and the opportunities you gameplanned for aren’t there as a result.
Even Payton and Brees had games that started off ugly and stayed ugly, but more often than not that elite pairing of HC/QB with good blocking up front opened the door to some excellent sequential play calling.