And we don’t know yet the long-term safety of off-label use of those drugs.
I know several people on that ish and they all look sickly and anorexic. And, not a single one of them have changed their lifestyle. Still eating out all the time and drinking heavily multiple times per week.
Plus you have to stay on it if you want to stay skinny. Once you stop, without significant lifestyle overhaul (which most are too lazy/undisciplined to do) you’ll just pack the weight back on.