I saw this morning that JP Morgan Chase is saying that it will be a local disruption/problem for the Baltimore economy but that it should not be a big issue for the broader economy/supply chain. The biggest issue is cars as Baltimore is the largest port for car imports, but most imported cars are apparently driven over the Canadian and Mexican borders. Plus, the other East Coast ports have the capacity to handle the traffic that would have gone to Baltimore.
Obviously Chase has some interest in making things sound good, but their explanations sound reasonable.