The Science of Fasting

CapitalCitySaint said
Also, total side rant but this is a good enough thread for its appropriateness.

I learned that yet another one of my friends started on Ozempic recently. She is petite. Tiny. She has VERY slight belly pudge (she’s never had kids) & is mid 40’s. I asked why she got on it & her response was “nothing works”.

She is middle-aged and we have all kinds of hormone fluctuations at this point, works a desk job, commutes 1 hour each way to work several times per week & is sporadic in the gym & goes at most 4x on a good week - and the biggest thing - drinks like a fish! Like a few glasses of wine most nights and many on weekends.

I guess it just bugs me because every woman I know on it, says nothing was working yet have not made any changes to lifestyle. Like why did you think doing what you’ve been doing was going to work? Your gym routine without changing anything else like you did in your 20’s will NOT work anymore. They all still eat out frequently, make modest efforts at the gym & still drink like college kids.

It’s crazy because we still don’t know long term safety for off-label use in people that weren’t overweight to begin with and don’t have a legitimate metabolic condition.

Don’t get me wrong, I’d love to eat like a garbage can & drink like a fish and still lose weight but at the end of the day, being skinny is not the same as being healthy.

Also, it made me realize how many ppl have moderate alcohol dependence. The fact that none of the women I know will give up their booze for their health is bizarre. I’d like to say men, too but I don’t know any men on ozempic.

Le sigh….

My Wife is on a Maintenace dose. She's lost about 50 pounds on it. She cut drinking wine way back when she first got started. Ozempic helps curb her appetite and slows down how quickly her body metabolizes food. She has slowly ramped back up her wine consumption, but does still eat a lot less. She is more active and has more energy since the weight loss. While she was never pre-diabetic, her fasting blood sugar was high normal and now is comfortably in the normal range.

Her grandfather is a diabetic, and her father was pre-diabetic and got on ozempic, lost 40 or 50 pounds, and now his fasting blood sugar is in the normal range, the insurance will not pay for his meds anymore, so he pays out of pocket.

Both her and her father has GI issues initially, but learned diet influenced that side effect (fried and greasy food + Ozempic) and as long as they moderate/remove those foods don't have the GI side effects.

I do agree that being skinny does not mean you are healthy, but obesity really is a killer, so skinny people with bad lifestyle habits are less unhealthy than heavier people with bad lifestyle habits.

I really feel like the ozempic and alcohol consumption are separate issues though. However, I totally agree there are a lot of people with moderate alcohol dependence.

I would speculate that you don't see as many [middle-aged] men on ozempic, because they are on Testosterone, which helps increase their metabolism and lose weight/maintain current weight.