I mean we saw that happen today. Dallas' only touchdown came on a grossly whiffed tackle because TOP at that point was grossly out of balance due to how fast the Saints were scoring. Mathieu ended up having to go to the locker room to get an IV because of how out of gas he was.
What did Kubiak do? Slowed the game down, started having 5 yard run plays and longer drives. Defense was able to get their legs back. Dallas then scored just two field goals the rest of the game.