If he got the defense together and told them to focus on Philly's only real remaining pass catcher, they clearly did not hear him. Goedert broke free nearly immediately after the ball was snapped with Harris several yards behind him and nobody else got close for 55 yards.
Howden did not take out Harris. Harris cut up and into the collision between Howden and Lattimore. It was irrelevant because he was already beat. Besides, Howden wouldn't have had Lattimore crossing in front of him that way if they had been in zone.