Hypothetical: If we're 2-4 and lose to Denver on national TV, is DA fired?

It makes no sense to fire a coach mid-season in the NFL. All it does is satiate the blood lust some fans have for DA's head.

Changing coaches isn't going to turn this team into a playoff team this year if they aren't already and all you might accomplish is getting worse draft picks. Let him play out the season and then go from there.