I mean I'm really more concerned with the being unreasonably cruel to a highly intelligent animal, but I know there are risks involved with the work. I'm not sure COVID was really related to labs, and tend to think it really was just something that occured in nature, but I haven't spent a lot of time looking into it so maybe it is linked.
Anway, I do know for a fact that some of the stuff in the Dr. Mary's Monkey book shown above is true. I don't know about all the links to the Kennedy assassination or David Ferry/the CIA/Bay of Pigs, but I do know that the Polio vaccine (the scratch vaccine) which was being worked on at Tulane was contaminated by the Simian Virus 40 (SV40) and that as a result SV 40 infected humans. It didn't really do much as far as making them sick. Except that there is research out there that infection by SV 40 through the Polio vaccine made people more likely to contract Mesothelioma. They think it weakened cell walls in the mesothelial cells that line the lung which allowed asbestos fibers to more easily penetrate them and cause mutations that lead to mesothelioma.
Anyway, as far as use of monkeys, I've seen things showing that computer models work just as well, maybe better. But, I'm honestly not sure if there are things that require the use of monkeys. But, I do think that they shouldn't do it unless it's absolutely necessary. I don't know, maybe I watched Project X with Matthew Broderick too many times as a kid.
Edit: On a side note, I once went into the infectious disease lab that Tulane had on the roof of Charity Hospital pre-Katrina. There were all sorts of nasty viruses stored in there to be used in research to find vaccines.