Determining whether the LSD a tripper takes is completely 100% sure is extremely difficult and the purer, more unfiltered the type of compounds one takes with acid, usually the stronger and more potent its going to be. I don't think the majority of the hippies living in Haight-Ashbury in the late 60's were knowledgable chemistry majors before they decided to follow Dr. O'Leary's advice about "tuning in, turning on, and dropping out", O'Leary later on came to regret that last part of his phrase because it got interpreted as wasting your life away by getting high on psychedelic drugs, don't work or contribute to society and live on SS payments or your parents' money in some underground, alternative would-be futuristic society.