Keys to the Rams: RUN THE DANG BALL
I agree with most of what has already been posted. I'll add that they need to shut down Kyren Williams. The Rams will run the ball until you make them stop. The Saints couldn't do that last year and that's what really frees up Kupp and Nacua.
Last year the Saints ran the ball 16 times. The Rams ran the ball 32 times. You have to make them one dimensional (like they did to us).