Round 3: Marburg Virus (1 Viewer)

Optimus Prime

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Never heard of this virus before
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After the coronavirus pandemic and the rise of monkeypox cases, news of another virus can trigger nerves globally.

The highly infectious Marburg virus has been reported in the West African country of Ghana this week, according to the World Health Organization.


Two unrelated people died after testing positive for Marburg in the southern Ashanti region of the country, the WHO said Sunday, confirming lab results from Ghana’s health service.

The highly infectious disease is similar to Ebola and has no vaccine.


Health officials in the country say they are working to isolate close contacts and mitigate the spread of the virus, and the WHO is marshaling resources and sending specialists to the country.

“Health authorities have responded swiftly, getting a head start preparing for a possible outbreak. This is good because without immediate and decisive action, Marburg can easily get out of hand,” said the WHO’s regional director for Africa, Matshidiso Moeti.


Fatality rates from the disease can reach nearly 90 percent, according to the WHO.


Here’s what we know about the virus:


What is the Marburg virus?


Marburg is a rare but highly infectious viral hemorrhagic fever and is in the same family as Ebola, a better-known virus that has plagued West Africa for years.


The Marburg virus is a “genetically unique zoonotic … RNA virus of the filovirus family,” according to the Centers for Disease Control and Prevention. “The six species of Ebola virus are the only other known members of the filovirus family.”

Fatality rates range from 24 percent to 88 percent, according to the WHO, depending on the virus strain and quality of case management.


Marburg has probably been transmitted to people from African fruit bats as a result of prolonged exposure from people working in mines and caves that have Rousettus bat colonies. It is not an airborne disease.


Once someone is infected, the virus can spread easily between humans through direct contact with the bodily fluids of infected people such as blood, saliva or urine, as well as on surfaces and materials.

Relatives and health workers remain most vulnerable alongside patients, and bodies can remain contagious at burial…….

 
I think it's going to be hard for a non airborne virus to cause anything near the type of issues that we had with covid.

Sure the disease is far worse, but it's much easier to avoid getting it.

Hopefully we never get one of these ebola type virus mutate to become airborne.
 
Read the book Hot Zone if you want to know about Ebola and Marburg

We had an outbreak in the US at a primate facility and got lottery lucky. Ebola Reston wiped out the primates in the facility and they know that it infected at least one person (if memory serves) who was out in public but it seems that this is the only strain of Ebola that killed primates and was asymptomatic in humans. Ebola Reston was especially brutal to the primates so we really dodged a bullet there
 
Read the book Hot Zone if you want to know about Ebola and Marburg

We had an outbreak in the US at a primate facility and got lottery lucky. Ebola Reston wiped out the primates in the facility and they know that it infected at least one person (if memory serves) who was out in public but it seems that this is the only strain of Ebola that killed primates and was asymptomatic in humans. Ebola Reston was especially brutal to the primates so we really dodged a bullet there

Read it.

Was a huge "infectious disease" follower for many years. Found the biology behind it all quite fascinating.

Then covid hit.

I cannot read, listen or watch shows about infectious disease right now. I think once we get past Sars COV2, ill be able to do again as im slowly digesting bits here and there. But my affinity for these pathogens is pretty much gone.
 
Read the book Hot Zone if you want to know about Ebola and Marburg

We had an outbreak in the US at a primate facility and got lottery lucky. Ebola Reston wiped out the primates in the facility and they know that it infected at least one person (if memory serves) who was out in public but it seems that this is the only strain of Ebola that killed primates and was asymptomatic in humans. Ebola Reston was especially brutal to the primates so we really dodged a bullet there
The series on Nat Geo based on the book was really good.

There was a sequel that covered the Anthrax scare that happened right around 9/11 where lab-created Anthrax was created and mailed to senators, news anchors, etc.

If you have Hulu, I believe that the Anthrax series is available.

Unlike Anthrax, which is easily treatable if caught in time, Ebola and Marburg have little to no vaccine availability.
 
Isn't the transmission window for Ebola really short? Making it slow to spread? Is Marburg the same way? Or am I thinking of something different?
 
Isn't the transmission window for Ebola really short? Making it slow to spread? Is Marburg the same way? Or am I thinking of something different?
It's around 20 or so days. It's slow to spread because it kills its hosts quickly and also has a more difficult route of transmission- unlike airborne viruses. There was a case here in Dallas several years ago that had everyone panicking.
 
It's around 20 or so days. It's slow to spread because it kills its hosts quickly and also has a more difficult route of transmission- unlike airborne viruses. There was a case here in Dallas several years ago that had everyone panicking.

Marbug or Ebola?

I dont recall any Marburg in the US. I do remember the Ebola outbreak around 2016 or so.

Marbug and Ebola are similar but not exactly same. Same family of virus ( filovirus ) but not quite the same. IIRC there are like 5 different strains of Ebola with 3 infectious to humans ( 2 are non-infectious to humans ).

Marburg has 2 strains and both can infect humans.
 
You don’t hear much about the Flu Virus anymore. Are we completely over that now?

How many of these shots I’m going to need?
 
The two things that would alarm me the most would be airborne and asymptomatic spread.

I mean dont get me wrong Ebola/Marbug are terrifying to think about having, but in terms of worrying about it actually happening, it is thankfully low on the list.

I know viruses can swap genetic material if more than one is present in the same host, but is that limited to within virus families coronavirus/filovirus? Or can it occur across families?
 
according to u.s. congressional testimony from a former colleague of ustinov's, the ussr had aerosolized marburg for deployment in mirv warheads

relevant portion of congressional record from 12 mar 1998 (long read)
 

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