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Diet gurus have been touting calorie in/calorie out since forever as if that's meaningful .... and yet, those who struggle with weight continue to struggle. Biology is biology but people need practical solutions; so to me, the argument about CICO is moot.I listened to this a while back and forgot to post (or maybe posted it and forgot i did). Anyway, it's an interesting story that describes the interactions of overfeeding with a mixed diet. If I understand properly the main reason that you lose weight going to a low carb diet is only the calorie restriction. Since you aren't overfeeding as much, you are burning more fat rather than storing it.
For the person whose weight is a constant battle, they are NOT going to count calories their entire life. It's just an untenable way to live your life. The trick is to find the "technique" you can incorporate seamlessly into your lifestyle without becoming obsessed about food.
Once I caught onto low carb, it made me re-think things like how much bread I ate. For instance, I love bread but when I think of it as merely a "meat holder", well, there's a LOT of bread that I can cut out that I don't even miss that we eat just because of convenience and gives us very little nutritional payoff: Those stale hamburger buns, tasteless wheat bread, bland pizza dough. If I want to lose weight, I have to go WAY beyond that; but I can easily maintain by just "little" things like that.
Anyway, I don't like to waste time or effort on the scientific/academic argument of caloric energy, I'd rather focus on ways to turn what I've learned into improving my eating habits.